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Terry Wyatt Getty Images for Stand Up To Cancer
Stand Up To Cancer Telecast 2025
NASHVILLE, TENNESSEE - AUGUST 09: In this photo released on August 11, 2025 A view of the venue during the Stand Up To Cancer Telecast 2025 at The Pinnacle on August 09, 2025 in Nashville, Tennessee. (Photo by Terry Wyatt/Getty Images for Stand Up To Cancer)
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Terry Wyatt Getty Images for Stand Up To Cancer
NASHVILLE, TENNESSEE - AUGUST 09: In this photo released on August 11, 2025 Sheryl Crow performs on stage during the Stand Up To Cancer Telecast 2025 at The Pinnacle on August 09, 2025 in Nashville, Tennessee. (Photo by Terry Wyatt/Getty Images for Stand Up To Cancer)
Stand Up To Cancer® (SU2C) will air its ninth biennial one-hour, commercial-free special simultaneously on over 30 participating media platforms across the United States on Friday, August 15 at 8 p.m. ET and PT / 7 p.m. CT. All four major U.S. broadcast networks will carry the show, with broadcasters donating prime time slots to support the cause. The telecast will also be available to watch on-demand across multiple digital and streaming platforms, ensuring broad and flexible access to this one-night-only event.
This year’s event promises an unforgettable night of music and star-studded moments in support of groundbreaking cancer research. Featured performances include Jonas Brothers, Noah Cyrus, Gavin DeGraw, Marcus King, Brothers Osborne, Jon Pardi, Jelly Roll, Dan + Shay and CeCe Winans, joined by Nashville Community Gospel Choir in a musical celebration of SU2C’s mission and Nashville’s rich legacy of storytelling and community.
Additional talent lending their help to raise critical funds for cancer research include pre-taped segments from Kevin Bacon, Jamie Foxx, Tim McGraw, Zoe Saldaña, Reese Witherspoon and Keith Urban. Grammy® Award-winning artist Sheryl Crow will serve as the evening’s host and also perform, along with remarks by SU2C co-founder Katie Couric.
This marks the first time that the telecast will be broadcast from Nashville, taking place at The Pinnacle, a premier venue in the heart of Music City.
Telecast viewers will also hear from leading SU2C-funded researchers about recent advances and why continued support is vital in the fight against this disease. From early detection to new treatment approaches, many survivors' stories reflect the real-world impact of SU2C-funded research and the hope it brings to patients and families.
As a lead-up to the televised special, SU2C has launched the #Up2Us to #StandUpToCancer campaign, which runs through Sunday, August 31. Now in its fifth year, this month-long fundraising initiative brings together creators from across Twitch, TikTok, Facebook, and YouTube to support groundbreaking cancer research. The campaign features diverse livestream content, from gaming to other engaging genres. Creators will host fundraising streams to raise awareness and support SU2C’s mission to fund research aimed at detecting, treating, and ultimately curing all cancers. Notable participating streamers and creators include Tess Bohne, Neebs Gaming, Trisha Hershberger, The Jang, KandidlyKayla, Stormfall33, and Khleo Thomas. Additionally, SMOSH and Marissa Hill are among the YouTube creators attending the SU2C telecast.
For more information, visit StandUpToCancer.org, Instagram, TikTok, Twitter, Facebook, and YouTube.